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Strong Evidence

What ADHD Is (and Isn't)

ADHD (Attention Deficit Hyperactivity Disorder) is a neurodevelopmental condition affecting how the brain regulates attention, activity, and impulses. It's not about being naughty, lazy, or badly parented - it's about brain differences.

The clinical definition

According to the DSM-5-TR (the diagnostic manual used internationally), ADHD is characterised by a persistent pattern of inattention and/or hyperactivity-impulsivity that:

  • Interferes with functioning or development
  • Was present before age 12 (even if not diagnosed until later)
  • Is present in two or more settings (e.g., home and school)
  • Is not better explained by another condition
ADHD is...
  • A neurodevelopmental condition present from early childhood
  • A difference in brain development affecting self-regulation
  • Highly heritable (approximately 74% genetic component)
  • Associated with differences in dopamine and noradrenaline pathways
  • Characterised by difficulties with attention, impulsivity, and/or hyperactivity
  • A spectrum - severity and presentation vary widely
  • Treatable with environmental support, behavioural strategies, and sometimes medication
  • Often co-occurring with other conditions (anxiety, autism, learning difficulties)
ADHD is not...
  • Caused by poor parenting, too much screen time, or sugar
  • A lack of willpower, laziness, or bad behaviour
  • Something children "grow out of" (though presentation changes with age)
  • A modern invention or overdiagnosed (rates are consistent globally)
  • Just about hyperactivity (inattentive presentations are common)
  • A male condition (girls are frequently underdiagnosed)
  • An excuse for bad behaviour
  • A barrier to success (many people with ADHD thrive with the right support)

What the research tells us

Strong Evidence

ADHD affects approximately 5-7% of children worldwide

Meta-analyses of prevalence studies (Polanczyk et al., 2015)

Strong Evidence

Heritability is approximately 74%, making it one of the most heritable psychiatric conditions

Twin and family studies (Faraone & Larsson, 2019)

Strong Evidence

Brain imaging shows differences in frontal regions, basal ganglia, and cerebellum

Neuroimaging meta-analyses (Hoogman et al., 2017)

Strong Evidence

ADHD persists into adulthood in approximately 50-65% of cases

Longitudinal studies (Faraone et al., 2021)

Strong Evidence

Co-occurrence with other conditions is the rule rather than the exception

Clinical guidelines (NICE NG87, AAP 2019)

Brain differences in ADHD

Brain imaging studies have identified consistent differences in people with ADHD. These are subtle differences in size and function - not damage or defects.

Prefrontal Cortex
Executive functions, planning, impulse control

Slightly smaller volume; matures approximately 2-3 years later

Basal Ganglia
Movement, reward processing, habit formation

Reduced volume in caudate and putamen regions

Cerebellum
Motor coordination, timing, cognitive processing

Reduced volume, particularly in posterior regions

Dopamine Pathways
Motivation, reward, attention regulation

Less efficient dopamine transmission and reuptake

Why "deficit" isn't the whole story

The term "Attention Deficit" is somewhat misleading. People with ADHD don't have less attention - they have difficulty regulating attention.

This is why someone with ADHD can focus intensely on interesting activities (sometimes called "hyperfocus") while struggling with tasks they find boring or unrewarding. The challenge isn't attention itself - it's the ability to direct attention voluntarily, especially when motivation is low.

Many researchers and advocates prefer terms like "attention regulation difficulty" or emphasise that ADHD involves differences in executive function more broadly.

The neuroscience in brief

Dopamine and noradrenaline are neurotransmitters (chemical messengers) that play key roles in attention, motivation, and executive function. In ADHD, these systems work less efficiently.

Dopamine is involved in reward processing and motivation. Lower dopamine activity can make it harder to sustain effort on tasks that aren't immediately rewarding - even when you know they're important.

Noradrenaline helps with alertness and filtering out distractions. When noradrenaline signalling is less efficient, it's harder to maintain focus and ignore irrelevant information.

This is why ADHD medications (both stimulants and non-stimulants) work by increasing the availability of these neurotransmitters in the brain.