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N
Mixed Evidence

Special Diets

Evidence and cautions for elimination diets, gluten/casein-free, and other special dietary approaches.

Important to know:

Restrictive diets carry risks including nutritional deficiencies and worsening relationship with food. Always consult a healthcare professional before starting, especially for children who are already picky eaters.

Common special diets reviewed

Gluten-free/Casein-free (GFCF)
Mixed Evidence
Eliminates gluten (wheat protein) and casein (dairy protein).

The claim:

That these proteins cause autism symptoms through opioid-like effects or leaky gut.

What research shows:

  • Cochrane review found insufficient evidence to recommend
  • Some small studies show benefit, but methodology is often poor
  • No evidence for the proposed mechanisms
  • May help a small subset, but no way to predict who

Risks:

  • Nutritional deficiencies (calcium, vitamin D, fibre)
  • Social restriction around food
  • Expense
  • False hope

Our view: Not recommended as routine. If trying, do so with dietitian support and for a time-limited trial.

Feingold Diet / Additive-free
Emerging Evidence
Eliminates artificial colours, flavours, and certain preservatives.

The claim:

That artificial additives cause or worsen ADHD symptoms.

What research shows:

  • Southampton studies showed small effects of colours on some children
  • UK has stricter regulations than US partly due to this research
  • Effect sizes are small
  • Not all children are affected

Risks:

  • Modest restrictions, relatively low risk
  • Can become overly restrictive

Our view: Reasonable to try if you notice patterns. UK foods already have fewer additives. Don't expect major changes.

Few Foods / Elimination Diet
Emerging Evidence
Removes most foods, then reintroduces one at a time to identify triggers.

The claim:

That identifying and removing trigger foods reduces symptoms.

What research shows:

  • Some studies show benefit for some children
  • NICE notes limited evidence and no long-term data
  • Very difficult to implement properly
  • Requires significant family commitment

Risks:

  • Nutritional deficiencies if prolonged
  • Extremely restrictive
  • Can worsen picky eating
  • Social isolation around food

Our view: Only consider with dietitian supervision. Not a first-line approach.

Ketogenic Diet
Emerging Evidence
Very low carbohydrate, high fat diet that induces ketosis.

The claim:

That ketones provide better brain fuel and reduce symptoms.

What research shows:

  • Strong evidence for epilepsy (used medically)
  • Preliminary research in autism, mostly animal studies
  • Very limited human data for ADHD/autism

Risks:

  • Nutritional concerns
  • Difficult to maintain
  • Not suitable for children without medical supervision

Our view: Not recommended for ADHD/autism outside of medical research settings.

Sugar Elimination
Not Supported
Removing or significantly reducing sugar intake.

The claim:

That sugar causes hyperactivity.

What research shows:

  • Multiple controlled studies show no sugar-behaviour link
  • Perceived effects are likely expectation effects
  • Exciting events with sugar (parties) confuse the picture

Risks:

  • Minimal if done moderately
  • Can become overly restrictive

Our view: Reducing sugar is reasonable for general health, but don't expect ADHD symptom improvement.

Before trying any restrictive diet

1

Consult a healthcare professional

Discuss with GP, paediatrician, or dietitian before starting restrictive diets.

2

Assess current nutritional status

Ensure baseline nutrition is adequate. Test for deficiencies if relevant.

3

Set clear goals and timeline

What improvement are you looking for? How long will you trial? How will you assess?

4

Plan for nutritional adequacy

How will you replace eliminated nutrients? Consider supplementation.

5

Consider the whole family

Who will follow the diet? How will you manage social situations?

6

Track systematically

Food diary and symptom tracking to objectively assess effects.

Warning signs to stop
Weight loss or failure to gain weight
Nutritional deficiencies appearing
Worsening relationship with food
Increasing restriction or food fear
Social isolation around food
Significant family stress
No improvement after adequate trial
Child is distressed by the diet

What guidelines say

NICE NG87 (ADHD)
  • Ask about foods/drinks that appear to influence behaviour
  • Consider food diary if clear link suspected
  • Dietitian referral if food diary supports dietary management
  • Note: limited evidence for "few foods" diet
Cochrane Reviews
  • GFCF diet: insufficient evidence to recommend
  • Artificial colours: small effects in some children
  • Few foods diet: limited evidence, difficult to implement
The key insight

Special diets are not first-line treatments. Evidence is limited, risks are real, and better-supported interventions exist. If you want to try a dietary approach, focus on overall diet quality first, and only consider elimination with professional guidance.

  • Most special diets have limited evidence for ADHD/autism specifically
  • Risks include nutritional deficiency and worsening relationship with food
  • If trying, do so with professional guidance and a clear plan
  • Time-limited trials with objective tracking are better than indefinite restriction
  • Focus on overall diet quality rather than elimination approaches